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Search Results for " sodium channel inhibitor 1 "

20

Compounds

Cat No. Product Name Synonyms Targets
T12948 Sodium Channel inhibitor 1 Others
Sodium Channel inhibitor1 is a novel and selective voltage-gated sodium channel for pain treatment. (IC50 Value of 0.16 uM and 0.41 uM for Na v1.7, V hold-90mV and Na v1.7, V hold-90mV)
T12181 NaV1.7 inhibitor-1 Sodium Channel
NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).
T12931 SLC13A5-IN-1 Stearoyl-CoA Desaturase (SCD)
SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells).
T0386L Ropivacaine LEA-103 HCl Potassium Channel , Sodium Channel
Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.
T0386 Ropivacaine hydrochloride Ropivacaine monohydrochloride Potassium Channel , Sodium Channel
Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity.
TN6713 6-Benzoylheteratisine Heteratisan-14-one, 6-(benzoyloxy)-20-ethyl-8-hydroxy-1-methoxy-4-meth Sodium Channel
6-Benzoylheteratisine (Heteratisan-14-one, 6-(benzoyloxy)-20-ethyl-8-hydroxy-1-methoxy-4-meth) is a Aconitum alkaloid. It can inhibits voltage-gated Na+ channels in rat brain synaptosomes
T6856 Halofuginone Tempostatin,empostatin,RU-19110 Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
T8579 Nav1.8-IN-1 5-(4-Chlorophenyl)-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]pyridine-3-carboxamide,CHEMBL1270208 Sodium Channel
Nav1.8-IN-1 (CHEMBL1270208) is an inhibitor of human NaV1.8
T6645 Ropivacaine hydrochloride monohydrate Ropivacaine HCl,Ropivacaine HCl monohydrate,LEA 103,LEA-103 HCl Potassium Channel , Sodium Channel
Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.
T3524 Halofuginone hydrobromide Tempostatin,RU-19110 (hydrobromide),Stenorol Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
T50030 1-(2,4-difluorophenyl)guanidine hydrochloride Others
1-(2,4-difluorophenyl)guanidine hydrochloride is a compound that is a potent and selective inhibitor of the voltage-gated sodium channel Nav1.7, a key player in pain signaling. It is therefore able to reduce pain signali...
T81134 Sodium Channel inhibitor 4 Sodium Channel
Sodium Channel Inhibitor 4 is a compound that functions as a sodium channel inhibitor [1].
T80533 Pterinotoxin-2 Sodium Channel
Pterinotoxin-2 is a peptide toxin that acts as a sodium channel inhibitor [1].
T80534 Pterinotoxin-1 Sodium Channel
Pterinotoxin-1 is a peptide toxin that functions as an inhibitor of sodium channels [1].
T79280 Nav1.3 channel inhibitor 1 Sodium Channel
Nav1.3 Channel Inhibitor 1 (Compound 15b) is a state-dependent inhibitor of the voltage-gated sodium channel Na v 1.3, with an IC50 value of 20 nM. It has the ability to cross the blood-brain barrier, making it applicabl...
T80439 GTx1-15 Sodium Channel
GTx1-15, an inhibitor cystine knot (ICK) peptide, antagonizes the voltage-dependent calcium channel Cav3.1, as well as voltage-dependent sodium channels Nav1.3 and Nav1.7 [1].
T80451 Ceratotoxin-2 CcoTx2,β-TRTX-cm1b Sodium Channel
Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel inhibitor, demonstrating half maximal inhibitory concentrations (IC50) of 8 nM for Na v 1.2/β 1 and 88 nM for Na v 1.3/β 1 [1].
T61475 Ropivacaine mesylate
Ropivacaine mesylate, a long-acting amide local anaesthetic, is used for spinal block and effectively mitigates neuropathic pain. It achieves analgesia by reversibly inhibiting sodium ion influx in nerve fibers, thus blo...
T80452 Ceratotoxin-1 CcoTx1,β-TRTX-cm1a Sodium Channel
Ceratotoxin-1 (CcoTx1) is a peptide toxin that functions as an inhibitor of various voltage-gated sodium channel subtypes. It selectively inhibits Nav1.11, Nav1.2/β1, Nav1.4/β1, and Nav1.5/β1 with IC50 values of 523 nM...
T80169 ProTx-III μ-TRTX-Tp1a Sodium Channel
ProTx-III, a spider venom peptide derived from the Peruvian green velvet tarantula, functions as a selective and potent inhibitor of the voltage-gated sodium channel Na v 1.7, exhibiting an IC 50 of 2.1 nM. Characterized...

Compounds

Sodium Channel inhibitor 1
T12948
Synonym:
Target: Others
NaV1.7 inhibitor-1
T12181
Synonym:
Target: Sodium Channel
SLC13A5-IN-1
T12931
Synonym:
Target: Stearoyl-CoA Desaturase (SCD)
Ropivacaine
T0386L
Synonym: LEA-103 HCl
Target: Potassium Channel, Sodium Channel
Ropivacaine hydrochloride
T0386
Synonym: Ropivacaine monohydrochloride
Target: Potassium Channel, Sodium Channel
6-Benzoylheteratisine
TN6713
Synonym: Heteratisan-14-one, 6-(benzoyloxy)-20-ethyl-8-hydroxy-1-methoxy-4-meth
Target: Sodium Channel
Halofuginone
T6856
Synonym: Tempostatin,empostatin,RU-19110
Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Nav1.8-IN-1
T8579
Synonym: 5-(4-Chlorophenyl)-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]pyridine-3-carboxamide,CHEMBL1270208
Target: Sodium Channel
Ropivacaine hydrochloride monohydrate
T6645
Synonym: Ropivacaine HCl,Ropivacaine HCl monohydrate,LEA 103,LEA-103 HCl
Target: Potassium Channel, Sodium Channel
Halofuginone hydrobromide
T3524
Synonym: Tempostatin,RU-19110 (hydrobromide),Stenorol
Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
1-(2,4-difluorophenyl)guanidine hydrochloride
T50030
Synonym:
Target: Others
Sodium Channel inhibitor 4
T81134
Synonym:
Target: Sodium Channel
Pterinotoxin-2
T80533
Synonym:
Target: Sodium Channel
Pterinotoxin-1
T80534
Synonym:
Target: Sodium Channel
Nav1.3 channel inhibitor 1
T79280
Synonym:
Target: Sodium Channel
GTx1-15
T80439
Synonym:
Target: Sodium Channel
Ceratotoxin-2
T80451
Synonym: CcoTx2,β-TRTX-cm1b
Target: Sodium Channel
Ropivacaine mesylate
T61475
Synonym:
Target:
Ceratotoxin-1
T80452
Synonym: CcoTx1,β-TRTX-cm1a
Target: Sodium Channel
ProTx-III
T80169
Synonym: μ-TRTX-Tp1a
Target: Sodium Channel
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TargetMol